DMG-PEG 2000
DMG-mPEG2000
CAS: 160743-62-4
Molecular Formula: C122H242O50
DMG-PEG 2000 - Names and Identifiers
DMG-PEG 2000 - Physico-chemical Properties
| Molecular Formula | C122H242O50 |
| Molar Mass | 2509.2 |
| Storage Condition | -20 ℃, dry, sealed |
| In vitro study | NP-3 (0.05-1.6 mg/mL; 24 hours) does not decrease the cytotoxicity of cells in 293T, HepG2, A549, and HeLa cell lines, but the DPPC and DMG-PEG coated nanoparticles reduce cell cytotoxicity. In addition, the transfection efficiency of DPPC/DMG-PEG/(lPEI/DNA) nanoparticles (NP-3) in 293 cells is improved, and the maximum transfection efficiency (∼76% eGFP positive cells) is observed. |
| In vivo study | NP-3 (oral administration; 150 μg DNA per mouse; single dose) at 12, 24, and 36 h postadministration, luciferin substrate is intraperitoneally injected to verify its permeability. NP-3 group maintains high luciferase expression in the liver, lung, and intestine areas 12-24 h post-treatment.Additionally, NP-3 exhibits 1.5 times higher signal intensity than that of NP-1 or NP-2 group from 12 to 24 h postoral administration. |
DMG-PEG 2000 - Reference Information
| biological activity | DMG-PEG 2000 for the preparation of liposomes for siRNA delivery, the transfection efficiency can be improved. DMG-PEG 2000 can also be used for the preparation of lipid nanoparticles for oral delivery of plasmid DNA in vivo, DMG-PEG 2000 can improve the mucus permeability and delivery efficiency of nanoparticles. |
Last Update：2024-04-09 21:04:16
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Product Name: DMG-PEG 2000 Visit Supplier Webpage Request for quotationCAS: 160743-62-4
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Product Name: DMG-PEG 2000 Request for quotation
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Spot supply
Product Name: DMG-PEG 2000 Visit Supplier Webpage Request for quotationCAS: 160743-62-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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